Dr. Ken Ohmori
(Associate Professor, Graduate School of Science and Engineering, Tokyo Institute of Technology)

Synthetic Study on Polycyclic Bioactive Natural ProductsTechnical Achievement

Dr. Ohmori has developed novel synthetic approaches to densely functionalized polycyclic framework embedded in various bioactive natural products. One of major challenges is the total synthesis of the benanomicin-pradimicin antibiotics via the stereo-selective/specific pinacol cyclization transmitting the stereochemical information from an axial to centrals. This approach would serve as a general and practical synthetic way for highly-oxygenated polycyclic natural/unnatural compounds.